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» Gene Ontology Friendly Biclustering of Expression Profiles
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BMCBI
2011
13 years 8 days ago
Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in i
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
Paolo G. V. Martini, Davide Risso, Gabriele Sales,...
BMCBI
2005
112views more  BMCBI 2005»
13 years 5 months ago
Towards precise classification of cancers based on robust gene functional expression profiles
Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...
Zheng Guo, Tianwen Zhang, Xia Li, Qi Wang, Jianzhe...
IJDMB
2008
117views more  IJDMB 2008»
13 years 5 months ago
Scoring and summarising gene product clusters using the Gene Ontology
: We propose an approach for quantifying the biological relatedness between gene products, based on their properties, and measure their similarities using exclusively statistical N...
Spiridon C. Denaxas, Christos Tjortjis
BMCBI
2006
169views more  BMCBI 2006»
13 years 5 months ago
Finding biological process modifications in cancer tissues by mining gene expression correlations
Background: Through the use of DNA microarrays it is now possible to obtain quantitative measurements of the expression of thousands of genes from a biological sample. This techno...
Giacomo Gamberoni, Sergio Storari, Stefano Volinia
BMCBI
2011
13 years 6 days ago
Errors in CGAP xProfiler and cDNA DGED: the importance of library parsing and gene selection algorithms
Background: The Cancer Genome Anatomy Project (CGAP) xProfiler and cDNA Digital Gene Expression Displayer (DGED) have been made available to the scientific community over a decade...
Andrew T. Milnthorpe, Mikhail Soloviev