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» Gene function classification using Bayesian models with hier...
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BMCBI
2007
146views more  BMCBI 2007»
13 years 4 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2008
127views more  BMCBI 2008»
13 years 4 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
BMCBI
2005
178views more  BMCBI 2005»
13 years 4 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
NIPS
2008
13 years 5 months ago
Efficient Sampling for Gaussian Process Inference using Control Variables
Sampling functions in Gaussian process (GP) models is challenging because of the highly correlated posterior distribution. We describe an efficient Markov chain Monte Carlo algori...
Michalis Titsias, Neil D. Lawrence, Magnus Rattray
BMCBI
2005
103views more  BMCBI 2005»
13 years 4 months ago
Many accurate small-discriminatory feature subsets exist in microarray transcript data: biomarker discovery
Background: Molecular profiling generates abundance measurements for thousands of gene transcripts in biological samples such as normal and tumor tissues (data points). Given such...
Leslie Grate