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» Gene set analysis using principal components
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BCB
2010
175views Bioinformatics» more  BCB 2010»
12 years 11 months ago
Gene set analysis using principal components
We present a new method for identifying gene sets associated with labeled samples, where the labels can be case versus control, or genotype differences. Existing approaches to thi...
Isa Kemal Pakatci, Wei Wang, Leonard McMillan
BMCBI
2006
183views more  BMCBI 2006»
13 years 4 months ago
Mining gene expression data by interpreting principal components
Background: There are many methods for analyzing microarray data that group together genes having similar patterns of expression over all conditions tested. However, in many insta...
Joseph C. Roden, Brandon W. King, Diane Trout, Ali...
GPB
2010
231views Solid Modeling» more  GPB 2010»
13 years 1 months ago
Mining Gene Expression Profiles: An Integrated Implementation of Kernel Principal Component Analysis and Singular Value Decompos
The detection of genes that show similar profiles under different experimental conditions is often an initial step in inferring the biological significance of such genes. Visualiz...
Ferran Reverter, Esteban Vegas, Pedro Sánch...
JMLR
2010
163views more  JMLR 2010»
12 years 11 months ago
Dense Message Passing for Sparse Principal Component Analysis
We describe a novel inference algorithm for sparse Bayesian PCA with a zero-norm prior on the model parameters. Bayesian inference is very challenging in probabilistic models of t...
Kevin Sharp, Magnus Rattray