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BIOINFORMATICS
2008
104views more  BIOINFORMATICS 2008»
13 years 5 months ago
Gene set enrichment analysis using linear models and diagnostics
Assaf P. Oron, Zhen Jiang, Robert Gentleman
BMCBI
2008
129views more  BMCBI 2008»
13 years 5 months ago
Gene set enrichment analysis for non-monotone association and multiple experimental categories
Background: Recently, microarray data analyses using functional pathway information, e.g., gene set enrichment analysis (GSEA) and significance analysis of function and expression...
Rongheng Lin, Shuangshuang Dai, Richard D. Irwin, ...
BMCBI
2005
212views more  BMCBI 2005»
13 years 4 months ago
PAGE: Parametric Analysis of Gene Set Enrichment
Background: Gene set enrichment analysis (GSEA) is a microarray data analysis method that uses predefined gene sets and ranks of genes to identify significant biological changes i...
Seon-Young Kim, David J. Volsky
BMCBI
2010
154views more  BMCBI 2010»
13 years 5 months ago
Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data
Background: A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine which DNA-b...
Robert C. McLeay, Timothy L. Bailey
BMCBI
2010
167views more  BMCBI 2010»
13 years 5 months ago
Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of met
Background: Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment. While these lists represent an accurat...
Melissa J. Morine, Jolene McMonagle, Sinead Toomey...