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IJCAI
1989
13 years 7 months ago
Functional Representation of Designs and Redesign Problem Solving
gn problem can be abstractly characterized as a constrained function-to-structure mapping. The de­ sign task takes as input the specifications of the desired functions of a device...
Ashok K. Goel, B. Chandrasekaran
BMCBI
2008
145views more  BMCBI 2008»
13 years 5 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2008
114views more  BMCBI 2008»
13 years 5 months ago
Partial mixture model for tight clustering of gene expression time-course
Background: Tight clustering arose recently from a desire to obtain tighter and potentially more informative clusters in gene expression studies. Scattered genes with relatively l...
Yinyin Yuan, Chang-Tsun Li, Roland Wilson
BMCBI
2007
200views more  BMCBI 2007»
13 years 5 months ago
BNDB - The Biochemical Network Database
Background: Technological advances in high-throughput techniques and efficient data acquisition methods have resulted in a massive amount of life science data. The data is stored ...
Jan Küntzer, Christina Backes, Torsten Blum, ...
BMCBI
2007
166views more  BMCBI 2007»
13 years 5 months ago
How to decide which are the most pertinent overly-represented features during gene set enrichment analysis
Background: The search for enriched features has become widely used to characterize a set of genes or proteins. A key aspect of this technique is its ability to identify correlati...
Roland Barriot, David J. Sherman, Isabelle Dutour