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BMCBI
2008
115views more  BMCBI 2008»
13 years 4 months ago
Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson corre...
Jianchao Yao, Chunqi Chang, Mari L. Salmi, Yeung S...
BMCBI
2005
94views more  BMCBI 2005»
13 years 4 months ago
Reproducible Clusters from Microarray Research: Whither?
Motivation: In cluster analysis, the validity of specific solutions, algorithms, and procedures present significant challenges because there is no null hypothesis to test and no &...
Nikhil R. Garge, Grier P. Page, Alan P. Sprague, B...
BMCBI
2010
102views more  BMCBI 2010»
13 years 4 months ago
Quantized correlation coefficient for measuring reproducibility of ChIP-chip data
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
Shouyong Peng, Mitzi I. Kuroda, Peter J. Park
BMCBI
2007
151views more  BMCBI 2007»
13 years 4 months ago
A statistical method to incorporate biological knowledge for generating testable novel gene regulatory interactions from microar
Background: The incorporation of prior biological knowledge in the analysis of microarray data has become important in the reconstruction of transcription regulatory networks in a...
Peter Larsen, Eyad Almasri, Guanrao Chen, Yang Dai
BMCBI
2007
130views more  BMCBI 2007»
13 years 4 months ago
Reproducibility of microarray data: a further analysis of microarray quality control (MAQC) data
Background: Many researchers are concerned with the comparability and reliability of microarray gene expression data. Recent completion of the MicroArray Quality Control (MAQC) pr...
James J. Chen, Huey-miin Hsueh, Robert R. Delongch...