Our rapidly growing knowledge regarding genetic variation in the human genome offers great potential for understanding the genetic etiology of disease. This, in turn, could revolut...
Margaret J. Eppstein, Joshua L. Payne, Bill C. Whi...
Background: The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding pro...
Ross K. Shepherd, Theo H. E. Meuwissen, John A. Wo...
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Background: Genome-wide association studies (GWAS) based on single nucleotide polymorphisms (SNPs) revolutionized our perception of the genetic regulation of complex traits and di...
Background: With current technology, vast amounts of data can be cheaply and efficiently produced in association studies, and to prevent data analysis to become the bottleneck of ...