105 search results - page 3 / 21 » Graph-Kernels for the Comparative Analysis of Protein Active... |
BMCBI
2008
13 years 5 months ago
2008
Background: Recognizing similarities and deriving relationships among protein molecules is a fundamental requirement in present-day biology. Similarities can be present at various...
GCB
2004
Springer
13 years 10 months ago
2004
Springer
: We introduce the novel concept of graph alignment, a generalization of graph isomorphism that is motivated by the commonly used multiple sequence alignments. Graph alignments and...
BMCBI
2005
13 years 4 months ago
2005
Background: Several problems exist with current methods used to align DNA sequences for comparative sequence analysis. Most dynamic programming algorithms assume that conserved se...
BMCBI
2010
13 years 5 months ago
2010
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
BMCBI
2008
13 years 5 months ago
2008
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...