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BMCBI
2007
112views more  BMCBI 2007»
13 years 6 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
BMCBI
2004
87views more  BMCBI 2004»
13 years 6 months ago
Selection of informative clusters from hierarchical cluster tree with gene classes
Background: A common clustering method in the analysis of gene expression data has been hierarchical clustering. Usually the analysis involves selection of clusters by cutting the...
Petri Törönen
BMCBI
2007
154views more  BMCBI 2007»
13 years 6 months ago
h-Profile plots for the discovery and exploration of patterns in gene expression data with an application to time course data
Background: An ever increasing number of techniques are being used to find genes with similar profiles from microarray studies. Visualization of gene expression profiles can aid t...
Yvonne E. Pittelkow, Susan R. Wilson
CATA
2009
13 years 7 months ago
Nearest Shrunken Centroid as Feature Selection of Microarray Data
The nearest shrunken centroid classifier uses shrunken centroids as prototypes for each class and test samples are classified to belong to the class whose shrunken centroid is nea...
Myungsook Klassen, Nyunsu Kim
BMCBI
2010
153views more  BMCBI 2010»
13 years 6 months ago
Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering
Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
Eva Freyhult, Mattias Landfors, Jenny Önskog,...