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BMCBI
2006
165views more  BMCBI 2006»
13 years 5 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
KDD
2004
ACM
150views Data Mining» more  KDD 2004»
14 years 6 months ago
A framework for ontology-driven subspace clustering
Traditional clustering is a descriptive task that seeks to identify homogeneous groups of objects based on the values of their attributes. While domain knowledge is always the bes...
Jinze Liu, Wei Wang 0010, Jiong Yang
BMCBI
2008
134views more  BMCBI 2008»
13 years 5 months ago
Clustering cancer gene expression data: a comparative study
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...
Marcílio Carlos Pereira de Souto, Ivan G. C...
BMCBI
2006
203views more  BMCBI 2006»
13 years 5 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...
BMCBI
2007
140views more  BMCBI 2007»
13 years 5 months ago
From genes to functional classes in the study of biological systems
Background: With the popularisation of high-throughput techniques, the need for procedures that help in the biological interpretation of results has increased enormously. Recently...
Fátima Al-Shahrour, Leonardo Arbiza, Hern&a...