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BIOINFORMATICS
2007
66views more  BIOINFORMATICS 2007»
13 years 5 months ago
Gene expression network analysis and applications to immunology
We address the problem of using expression data and prior biological knowledge to identify differentially expressed pathways or groups of genes. Following an idea of Ideker et al...
Serban Nacu, Rebecca Critchley-Thorne, Peter Lee, ...
BMCBI
2004
180views more  BMCBI 2004»
13 years 5 months ago
Noise filtering and nonparametric analysis of microarray data underscores discriminating markers of oral, prostate, lung, ovaria
Background: A major goal of cancer research is to identify discrete biomarkers that specifically characterize a given malignancy. These markers are useful in diagnosis, may identi...
Virginie M. Aris, Michael J. Cody, Jeff Cheng, Jam...
ICDM
2005
IEEE
215views Data Mining» more  ICDM 2005»
13 years 11 months ago
CLUGO: A Clustering Algorithm for Automated Functional Annotations Based on Gene Ontology
We address the issue of providing highly informative and comprehensive annotations using information revealed by the structured vocabularies of Gene Ontology (GO). For a target, a...
In-Yee Lee, Jan-Ming Ho, Ming-Syan Chen
BMCBI
2010
92views more  BMCBI 2010»
13 years 5 months ago
Integrating gene expression and GO classification for PCA by preclustering
Background: Gene expression data can be analyzed by summarizing groups of individual gene expression profiles based on GO annotation information. The mean expression profile per g...
Jorn R. de Haan, Ester Piek, René C. van Sc...
BMCBI
2010
102views more  BMCBI 2010»
13 years 5 months ago
Quantized correlation coefficient for measuring reproducibility of ChIP-chip data
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
Shouyong Peng, Mitzi I. Kuroda, Peter J. Park