Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
Maria Rodriguez-Fernandez, Jose A. Egea, Julio R. ...
We present a technique to associate to stochastic programs written in stochastic Concurrent Constraint Programming a semantics in terms of a lattice of hybrid automata. The aim of ...
We apply the multi-agent system (MAS) platform to the task of biological network simulation. In this paper, we describe the simulation of signal transduction (ST) networks using t...
Salim Khan, Ravi Makkena, Foster McGeary, Keith S....
Abstract. Biological systems involving genetic reactions are large discrete event systems, and often contain certain species that occur in small quantities, and others that occur i...
Abstract. This paper combines three topics to which Amir Pnueli contributed significantly: the semantics of languages for concurrency, the semantics of statecharts, and reactive an...