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» HYPE Applied to the Modelling of Hybrid Biological Systems
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BMCBI
2006
194views more  BMCBI 2006»
13 years 5 months ago
Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
Maria Rodriguez-Fernandez, Jose A. Egea, Julio R. ...
CIE
2009
Springer
14 years 10 days ago
Stochastic Programs and Hybrid Automata for (Biological) Modeling
We present a technique to associate to stochastic programs written in stochastic Concurrent Constraint Programming a semantics in terms of a lattice of hybrid automata. The aim of ...
Luca Bortolussi, Alberto Policriti
ATAL
2003
Springer
13 years 11 months ago
A multi-agent system for the quantitative simulation of biological networks
We apply the multi-agent system (MAS) platform to the task of biological network simulation. In this paper, we describe the simulation of signal transduction (ST) networks using t...
Salim Khan, Ravi Makkena, Foster McGeary, Keith S....
HYBRID
2004
Springer
13 years 11 months ago
Dynamic Partitioning of Large Discrete Event Biological Systems for Hybrid Simulation and Analysis
Abstract. Biological systems involving genetic reactions are large discrete event systems, and often contain certain species that occur in small quantities, and others that occur i...
Natasha A. Neogi
BIRTHDAY
2010
Springer
13 years 3 months ago
Some Thoughts on the Semantics of Biocharts
Abstract. This paper combines three topics to which Amir Pnueli contributed significantly: the semantics of languages for concurrency, the semantics of statecharts, and reactive an...
David Harel, Hillel Kugler