Sciweavers

18 search results - page 1 / 4
» Haplotype Inference in Complex Pedigrees
Sort
View
RECOMB
2009
Springer
14 years 5 months ago
Haplotype Inference in Complex Pedigrees
Abstract. Despite the desirable information contained in complex pedigree datasets, analysis methods struggle to efficiently process these datasets. The attractiveness of pedigree ...
Bonnie Kirkpatrick, Javier Rosa, Eran Halperin, Ri...
BMCBI
2006
95views more  BMCBI 2006»
13 years 4 months ago
Estimate haplotype frequencies in pedigrees
Background: Haplotype analysis has gained increasing attention in the context of association studies of disease genes and drug responsivities over the last years. The potential us...
Qiangfeng Zhang, YuZhong Zhao, Guoliang Chen, Yun ...
ISAAC
2005
Springer
81views Algorithms» more  ISAAC 2005»
13 years 10 months ago
Complexity and Approximation of the Minimum Recombination Haplotype Configuration Problem
We study the complexity and approximation of the problem of reconstructing haplotypes from genotypes on pedigrees under the Mendelian Law of Inheritance and the minimum recombinant...
Lan Liu, Xi Chen, Jing Xiao, Tao Jiang
WABI
2010
Springer
170views Bioinformatics» more  WABI 2010»
13 years 2 months ago
Haplotypes versus Genotypes on Pedigrees
Abstract. Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping...
Bonnie Kirkpatrick
RECOMB
2011
Springer
12 years 7 months ago
Haplotype Reconstruction in Large Pedigrees with Many Untyped Individuals
Abstract. Haplotypes, as they specify the linkage patterns between dispersed genetic variations, provide important information for understanding the genetics of human traits. Howev...
Xin Li, Jing Li