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ESCIENCE
2007
IEEE
13 years 9 months ago
Grid-Enabling an Efficient Algorithm for Demanding Global Optimization Problems in Genetic Analysis
Abstract. We study the implementation on grid systems of an efficient algorithm for demanding global optimization problems. Specifically, we consider problems arising in the geneti...
Mahen Jayawardena, Sverker Holmgren
BMCBI
2008
186views more  BMCBI 2008»
13 years 5 months ago
Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
Min Zhang, Dabao Zhang, Martin T. Wells
BMCBI
2006
169views more  BMCBI 2006»
13 years 5 months ago
Comparative analysis of haplotype association mapping algorithms
Background: Finding the genetic causes of quantitative traits is a complex and difficult task. Classical methods for mapping quantitative trail loci (QTL) in miceuse an F2 cross b...
Phillip McClurg, Mathew T. Pletcher, Tim Wiltshire...
BMCBI
2008
122views more  BMCBI 2008»
13 years 5 months ago
Generating samples for association studies based on HapMap data
Background: With the completion of the HapMap project, a variety of computational algorithms and tools have been proposed for haplotype inference, tag SNP selection and genome-wid...
Jing Li, Yixuan Chen
BMCBI
2007
107views more  BMCBI 2007»
13 years 5 months ago
A general and efficient method for estimating continuous IBD functions for use in genome scans for QTL
Background: Identity by descent (IBD) matrix estimation is a central component in mapping of Quantitative Trait Loci (QTL) using variance component models. A large number of algor...
Francois Besnier, Örjan Carlborg