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JMLR
2010
133views more  JMLR 2010»
12 years 11 months ago
Hierarchical Cost-Sensitive Algorithms for Genome-Wide Gene Function Prediction
In this work we propose new ensemble methods for the hierarchical classification of gene functions. Our methods exploit the hierarchical relationships between the classes in diffe...
Nicolò Cesa-Bianchi, Giorgio Valentini
BMCBI
2010
109views more  BMCBI 2010»
13 years 4 months ago
Predicting gene function using hierarchical multi-label decision tree ensembles
Background: S. cerevisiae, A. thaliana and M. musculus are well-studied organisms in biology and the sequencing of their genomes was completed many years ago. It is still a challe...
Leander Schietgat, Celine Vens, Jan Struyf, Hendri...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
EVOW
2009
Springer
13 years 8 months ago
A Hierarchical Classification Ant Colony Algorithm for Predicting Gene Ontology Terms
Abstract. This paper proposes a novel Ant Colony Optimisation algorithm for the hierarchical problem of predicting protein functions using the Gene Ontology (GO). The GO structure ...
Fernando E. B. Otero, Alex Alves Freitas, Colin G....
CSB
2004
IEEE
173views Bioinformatics» more  CSB 2004»
13 years 8 months ago
Gene Ontology Friendly Biclustering of Expression Profiles
The soundness of clustering in the analysis of gene expression profiles and gene function prediction is based on the hypothesis that genes with similar expression profiles may imp...
Jinze Liu, Wei Wang 0010, Jiong Yang