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» High Performance Database Searching with HMMer on FPGAs
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IPPS
2007
IEEE
13 years 11 months ago
High Performance Database Searching with HMMer on FPGAs
1 Profile Hidden Markov Models (profile HMMs) are used as a popular bioinformatics tool for sensitive database searching, e.g. a set of not annotated protein sequences is compared...
Timothy F. Oliver, Leow Yuan Yeow, Bertil Schmidt
SC
2005
ACM
13 years 10 months ago
ClawHMMER: A Streaming HMMer-Search Implementation
The proliferation of biological sequence data has motivated the need for an extremely fast probabilistic sequence search. One method for performing this search involves evaluating...
Daniel Reiter Horn, Mike Houston, Pat Hanrahan
BMCBI
2005
152views more  BMCBI 2005»
13 years 4 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
HPDC
2006
IEEE
13 years 10 months ago
Exploring I/O Strategies for Parallel Sequence-Search Tools with S3aSim
Parallel sequence-search tools are rising in popularity among computational biologists. With the rapid growth of sequence databases, database segmentation is the trend of the futu...
Avery Ching, Wu-chun Feng, Heshan Lin, Xiaosong Ma...