One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
Background: In order to maintain the most comprehensive structural annotation databases we must carry out regular updates for each proteome using the latest profile-profile fold r...
Liam J. McGuffin, Richard T. Smith, Kevin Bryson, ...
Structural biology research places significant demands upon computing and informatics infrastructure. Protein production, crystallization and X-ray data collection require solutio...
Noel G. Faux, Anthony Beitz, Mark A. Bate, Abdulla...
High-throughput proteome annotation refers to the activity of extracting information from all proteins in a particular organism using bioinformatics software on a high performance ...
Atif Shahab, Danny Chuon, Toyotaro Suzumura, Wilfr...
We report results for the in-silico screening of a database of 10000 flexible compounds against various crystal structures of the thymidine kinase receptor complexed with 10 know...