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BMCBI
2008
114views more  BMCBI 2008»
13 years 9 months ago
Combining classifiers for improved classification of proteins from sequence or structure
Background: Predicting a protein's structural or functional class from its amino acid sequence or structure is a fundamental problem in computational biology. Recently, there...
Iain Melvin, Jason Weston, Christina S. Leslie, Wi...
BMCBI
2007
153views more  BMCBI 2007»
13 years 9 months ago
A new pairwise kernel for biological network inference with support vector machines
Background: Much recent work in bioinformatics has focused on the inference of various types of biological networks, representing gene regulation, metabolic processes, protein-pro...
Jean-Philippe Vert, Jian Qiu, William Stafford Nob...
BMCBI
2011
13 years 4 months ago
DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Jesse Eickholt, Xin Deng, Jianlin Cheng
EVOW
2007
Springer
14 years 1 months ago
Classification of Cell Fates with Support Vector Machine Learning
In human mesenchymal stem cells the envelope surrounding the nucleus, as visualized by the nuclear lamina, has a round and flat shape. The lamina structure is considerably deformed...
Ofer M. Shir, Vered Raz, Roeland W. Dirks, Thomas ...
CIBB
2008
13 years 11 months ago
Analysis of Kernel Based Protein Classification Strategies Using Pairwise Sequence Alignment Measures
Abstract. We evaluated methods of protein classification that use kernels built from BLAST output parameters. Protein sequences were represented as vectors of parameters (e.g. simi...
Dino Franklin, Somdutta Dhir, Sándor Pongor