Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Background: Single-pass, partial sequencing of complementary DNA (cDNA) libraries generates thousands of chromatograms that are processed into high quality expressed sequence tags...
Charu G. Kumar, Richard LeDuc, George Gong, Levan ...
Background -: Sequencing of EST and BAC end datasets is no longer limited to large research groups. Drops in per-base pricing have made high throughput sequencing accessible to in...
Stephen E. Diener, Thomas D. Houfek, Sam E. Kalat,...
This paper presents GMLE 1 , a generic and distributed framework for maximum likelihood evaluation. GMLE is currently being applied to astroinformatics for determining the shape o...
Travis J. Desell, Nathan Cole, Malik Magdon-Ismail...