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RECOMB
2006
Springer
10 years 1 months ago
Identifiability Issues in Phylogeny-Based Detection of Horizontal Gene Transfer
Prokaryotic organisms share genetic material across species boundaries by means of a process known as horizontal gene transfer (HGT). Detecting this process bears great significanc...
Cuong Than, Derek A. Ruths, Hideki Innan, Luay Nak...
BMCBI
2006
100views more  BMCBI 2006»
9 years 1 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight
BMCBI
2004
91views more  BMCBI 2004»
9 years 1 months ago
SIGI: score-based identification of genomic islands
Background: Genomic islands can be observed in many microbial genomes. These stretches of DNA have a conspicuous composition with regard to sequence or encoded functions. Genomic ...
Rainer Merkl
JCB
2007
145views more  JCB 2007»
9 years 1 months ago
Confounding Factors in HGT Detection: Statistical Error, Coalescent Effects, and Multiple Solutions
Prokaryotic organisms share genetic material across species boundaries by means of a process known as horizontal gene transfer (HGT). This process has great signi´Čücance for unde...
Cuong Than, Derek A. Ruths, Hideki Innan, Luay Nak...
BMCBI
2005
116views more  BMCBI 2005»
9 years 1 months ago
A computational approach for identifying pathogenicity islands in prokaryotic genomes
Background: Pathogenicity islands (PAIs), distinct genomic segments of pathogens encoding virulence factors, represent a subgroup of genomic islands (GIs) that have been acquired ...
Sung Ho Yoon, Cheol-Goo Hur, Ho-Young Kang, Yeoun ...
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