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» Identification of embryo specific human isoforms using a dat...
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JIB
2006
78views more  JIB 2006»
13 years 3 months ago
Identification of embryo specific human isoforms using a database of predicted alternative splice forms
Alternative splicing is one of the most important mechanisms to generate a large number of mRNA and protein isoforms from a small number of genes. Its study became one of the hot ...
Heike Pospisil
BMCBI
2007
118views more  BMCBI 2007»
13 years 3 months ago
A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of
Background: Most human genes produce several transcripts with different exon contents by using alternative promoters, alternative polyadenylation sites and alternative splice site...
Pierre de la Grange, Martin Dutertre, Margot Corre...
BMCBI
2007
180views more  BMCBI 2007»
13 years 3 months ago
Splicy: a web-based tool for the prediction of possible alternative splicing events from Affymetrix probeset data
Background: The Affymetrix™ technology is nowadays a well-established method for the analysis of gene expression profiles in cancer research studies. However, changes in gene ex...
Davide Rambaldi, Barbara Felice, Viviane Praz, Phi...
BMCBI
2007
148views more  BMCBI 2007»
13 years 3 months ago
p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data
Background: The p53 gene family consists of the three genes p53, p63 and p73, which have polyhedral non-overlapping functions in pivotal cellular processes such as DNA synthesis a...
Elisabetta Sbisà, Domenico Catalano, Giorgi...
ALMOB
2006
155views more  ALMOB 2006»
13 years 3 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg