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» Identification of replication origins in prokaryotic genomes
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BIB
2008
113views more  BIB 2008»
13 years 5 months ago
Identification of replication origins in prokaryotic genomes
The availability of hundreds of complete bacterial genomes has created new challenges and simultaneously opportunities for bioinformatics. In the area of statistical analysis of g...
Natalia V. Sernova, Mikhail S. Gelfand
BMCBI
2005
116views more  BMCBI 2005»
13 years 5 months ago
A computational approach for identifying pathogenicity islands in prokaryotic genomes
Background: Pathogenicity islands (PAIs), distinct genomic segments of pathogens encoding virulence factors, represent a subgroup of genomic islands (GIs) that have been acquired ...
Sung Ho Yoon, Cheol-Goo Hur, Ho-Young Kang, Yeoun ...
BMCBI
2006
156views more  BMCBI 2006»
13 years 5 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
BMCBI
2008
112views more  BMCBI 2008»
13 years 5 months ago
Evaluation of genomic island predictors using a comparative genomics approach
Background: Genomic islands (GIs) are clusters of genes in prokaryotic genomes of probable horizontal origin. GIs are disproportionately associated with microbial adaptations of m...
Morgan G. I. Langille, William W. L. Hsiao, Fiona ...
BMCBI
2008
123views more  BMCBI 2008»
13 years 5 months ago
Ori-Finder: A web-based system for finding oriCs in unannotated bacterial genomes
Background: Chromosomal replication is the central event in the bacterial cell cycle. Identification of replication origins (oriCs) is necessary for almost all newly sequenced bac...
Feng Gao, Chun-Ting Zhang