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» Identifying Chimerism in Proteins Using Hidden Markov Models...
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ESWA
2007
117views more  ESWA 2007»
13 years 5 months ago
An HMM for detecting spam mail
Hidden Markov Models, or HMMs for short, have been recently used in Bioinformatics for the classification of DNA or protein chains, giving rise to what is known as Profile Hidde...
José Gordillo, Eduardo Conde
BMCBI
2006
92views more  BMCBI 2006»
13 years 5 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
BMCBI
2004
108views more  BMCBI 2004»
13 years 5 months ago
Enhanced protein domain discovery using taxonomy
Background: It is well known that different species have different protein domain repertoires, and indeed that some protein domains are kingdom specific. This information has not ...
Lachlan James M. Coin, Alex Bateman, Richard Durbi...
BMCBI
2004
102views more  BMCBI 2004»
13 years 5 months ago
Detection of transposable elements by their compositional bias
Background: Transposable elements (TE) are mobile genetic entities present in nearly all genomes. Previous work has shown that TEs tend to have a different nucleotide composition ...
Olivier Andrieu, Anna-Sophie Fiston, Dominique Anx...
BMCBI
2010
123views more  BMCBI 2010»
13 years 10 days ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke