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CSIE
2009
IEEE
13 years 11 months ago
Identifying DNA Strands Using a Kernel of Classified Sequences
— Automated DNA sequencing produces a large amount of raw DNA sequence data that then needs to be classified, organized, and annotation. One major application is the comparison o...
Guillermo Tonsmann, David D. Pollock, Wanjun Gu, T...
BMCBI
2006
110views more  BMCBI 2006»
13 years 5 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen
BMCBI
2008
143views more  BMCBI 2008»
13 years 5 months ago
Automatic detection of exonic splicing enhancers (ESEs) using SVMs
Background: Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for S...
Britta Mersch, Alexander Gepperth, Sándor S...
BMCBI
2008
135views more  BMCBI 2008»
13 years 5 months ago
Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
Background: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-sca...
Hailong Meng, Edward Lenn Murrelle, Guoya Li
BMCBI
2008
132views more  BMCBI 2008»
13 years 5 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood