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JDCTA
2010
130views more  JDCTA 2010»
12 years 11 months ago
A Search Algorithm for Clusters in a Network or Graph
A novel breadth-first based structural clustering method for graphs is proposed. Clustering is an important task for analyzing complex networks such as biological networks, World ...
Dongming Chen, Jing Wang, Xiaodong Chen, Xiaowei X...
BMCBI
2007
202views more  BMCBI 2007»
13 years 4 months ago
ProtNet: a tool for stochastic simulations of protein interaction networks dynamics
Background: Protein interactions support cell organization and mediate its response to any specific stimulus. Recent technological advances have produced large data-sets that aim ...
Massimo Bernaschi, Filippo Castiglione, Alessandra...
TIT
2010
170views Education» more  TIT 2010»
12 years 11 months ago
Belief propagation estimation of protein and domain interactions using the sum-product algorithm
We present a novel framework to estimate protein-protein (PPI) and domain-domain (DDI) interactions based on a belief propagation estimation method that efficiently computes inter...
Faruck Morcos, Marcin Sikora, Mark S. Alber, Dale ...
BMCBI
2007
126views more  BMCBI 2007»
13 years 4 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne
BMCBI
2005
149views more  BMCBI 2005»
13 years 4 months ago
The PD-(D/E)XK superfamily revisited: identification of new members among proteins involved in DNA metabolism and functional pre
Background: The PD-(D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is o...
Jan Kosinski, Marcin Feder, Janusz M. Bujnicki