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» Identifying enrichment candidates in textbooks
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BMCBI
2010
101views more  BMCBI 2010»
13 years 5 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
COMPUTER
2006
84views more  COMPUTER 2006»
13 years 5 months ago
Testable, Reusable Units of Cognition
The educational content of a technical topic consists, ultimately, of elementary chunks of knowledge. Identifying and classifying such units -- Testable, Reusable Units of Cogniti...
Bertrand Meyer
BMCBI
2007
112views more  BMCBI 2007»
13 years 4 months ago
Inferring biological functions and associated transcriptional regulators using gene set expression coherence analysis
Background: Gene clustering has been widely used to group genes with similar expression pattern in microarray data analysis. Subsequent enrichment analysis using predefined gene s...
Tae-Min Kim, Yeun-Jun Chung, Mun-Gan Rhyu, Myeong ...
BMCBI
2010
125views more  BMCBI 2010»
13 years 5 months ago
A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins
Background: Several bioinformatic approaches have previously been used to find novel sites of ADAR mediated A-to-I RNA editing in human. These studies have discovered thousands of...
Mats Ensterö, Örjan Åkerborg, Dani...
BMCBI
2008
202views more  BMCBI 2008»
13 years 5 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...