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BMCBI
2002
110views more  BMCBI 2002»
13 years 4 months ago
Identifying functional relationships among human genes by systematic analysis of biological literature
Background: The availability of biomedical literature in electronic format has made it possible to implement automatic text processing methods to expose implicit relationships amo...
Yong-Chuan Tao, Rudolph L. Leibel
BMCBI
2005
114views more  BMCBI 2005»
13 years 4 months ago
Systematic analysis of human kinase genes: a large number of genes and alternative splicing events result in functional and stru
Background: Protein kinases are a well defined family of proteins, characterized by the presence of a common kinase catalytic domain and playing a significant role in many importa...
Luciano Milanesi, Mauro Petrillo, Leandra Sepe, An...
BMCBI
2008
202views more  BMCBI 2008»
13 years 4 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2008
138views more  BMCBI 2008»
13 years 4 months ago
Systematic identification of yeast cell cycle transcription factors using multiple data sources
Background: Eukaryotic cell cycle is a complex process and is precisely regulated at many levels. Many genes specific to the cell cycle are regulated transcriptionally and are exp...
Wei-Sheng Wu, Wen-Hsiung Li
BMCBI
2006
186views more  BMCBI 2006»
13 years 4 months ago
Systematic gene function prediction from gene expression data by using a fuzzy nearest-cluster method
Background: Quantitative simultaneous monitoring of the expression levels of thousands of genes under various experimental conditions is now possible using microarray experiments....
Xiaoli Li, Yin-Chet Tan, See-Kiong Ng