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BMCBI
2008
100views more  BMCBI 2008»
13 years 5 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
BMCBI
2007
157views more  BMCBI 2007»
13 years 5 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...
ALENEX
2001
215views Algorithms» more  ALENEX 2001»
13 years 7 months ago
An Empirical Study of a New Approach to Nearest Neighbor Searching
In nearest neighbor searching we are given a set of n data points in real d-dimensional space, d , and the problem is to preprocess these points into a data structure, so that give...
Songrit Maneewongvatana, David M. Mount
BMCBI
2008
170views more  BMCBI 2008»
13 years 5 months ago
A genetic approach for building different alphabets for peptide and protein classification
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Loris Nanni, Alessandra Lumini
KDD
2007
ACM
159views Data Mining» more  KDD 2007»
14 years 6 months ago
Local decomposition for rare class analysis
Given its importance, the problem of predicting rare classes in large-scale multi-labeled data sets has attracted great attentions in the literature. However, the rare-class probl...
Junjie Wu, Hui Xiong, Peng Wu, Jian Chen