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» Improvement in accuracy of multiple sequence alignment using...
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BMCBI
2006
139views more  BMCBI 2006»
9 years 2 months ago
Improvement in accuracy of multiple sequence alignment using novel group-to-group sequence alignment algorithm with piecewise li
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
Shinsuke Yamada, Osamu Gotoh, Hayato Yamana
IPPS
2003
IEEE
9 years 7 months ago
Using Hybrid Alignment for Iterative Sequence Database Searches
Progressive sequence model reļ¬nement by means of iterative searches is an effective technique for high sensitivity database searches and is currently employed in popular tools s...
Yuheng Li, Mario Lauria, Ralf Bundschuh
BMCBI
2007
153views more  BMCBI 2007»
9 years 2 months ago
Lower bounds on multiple sequence alignment using exact 3-way alignment
Background: Multiple sequence alignment is fundamental. Exponential growth in computation time appears to be inevitable when an optimal alignment is required for many sequences. E...
Charles J. Colbourn, Sudhir Kumar
BMCBI
2008
140views more  BMCBI 2008»
9 years 2 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
BMCBI
2005
132views more  BMCBI 2005»
9 years 2 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
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