10 search results - page 1 / 2 » Improvement of alignment accuracy utilizing sequentially con... |
BMCBI
2004
13 years 4 months ago
2004
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
BMCBI
2008
13 years 4 months ago
2008
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
BIBE
2005
IEEE
13 years 10 months ago
2005
IEEE
We have recently demonstrated (La et al, Proteins, 58:2005) that sequence fragments approximating the overall familial phylogeny, called phylogenetic motifs (PMs), represent a pro...
BMCBI
2002
13 years 4 months ago
2002
Background: Total sequence decomposition, using the web-based MASIA tool, identifies areas of conservation in aligned protein sequences. By structurally annotating these motifs, t...
BMCBI
2007
13 years 4 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...