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BMCBI
2010
110views more  BMCBI 2010»
13 years 3 months ago
Improvements to previous algorithms to predict gene structure and isoform concentrations using Affymetrix Exon arrays
Background: Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene...
Miguel A. Anton, Ander Aramburu, Angel Rubio
BMCBI
2010
99views more  BMCBI 2010»
13 years 4 months ago
Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays
Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
Yi Qu, Fei He, Yuchen Chen
BIB
2008
88views more  BIB 2008»
13 years 4 months ago
An overview of image-processing methods for Affymetrix GeneChips
We present an overview of image-processing methods for Affymetrix GeneChips. All GeneChips are affected to some extent by spatially coherent defects and image processing has a num...
Jose M. Arteaga-Salas, Harry Zuzan, William B. Lan...
RECOMB
2004
Springer
14 years 4 months ago
Computational identification of evolutionarily conserved exons
Phylogenetic hidden Markov models (phylo-HMMs) have recently been proposed as a means for addressing a multispecies version of the ab initio gene prediction problem. These models ...
Adam C. Siepel, David Haussler
JCB
2006
129views more  JCB 2006»
13 years 4 months ago
GenRate: A Generative Model that Reveals Novel Transcripts in Genome-Tiling Microarray Data
Genome-wide microarray designs containing millions to hundreds of millions of probes are available for a variety of mammals, including mouse and human. These genome tiling arrays ...
Brendan J. Frey, Quaid Morris, Timothy R. Hughes