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IJDMB
2006
86views more  IJDMB 2006»
13 years 4 months ago
Improving domain-based protein interaction prediction using biologically-significant negative dataset
: We propose a domain-based classification method to predict protein-protein interactions using probabilities of putative interacting domain pairs derived from both experimentally-...
Xiaoli Li, Soon-Heng Tan, See-Kiong Ng
BMCBI
2008
138views more  BMCBI 2008»
13 years 4 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
BMCBI
2007
102views more  BMCBI 2007»
13 years 4 months ago
A mixture of feature experts approach for protein-protein interaction prediction
High-throughput methods can directly detect the set of interacting proteins in yeast but the results are often incomplete and exhibit high false positive and false negative rates....
Yanjun Qi, Judith Klein-Seetharaman, Ziv Bar-Josep...
BMCBI
2010
98views more  BMCBI 2010»
13 years 4 months ago
An optimized TOPS+ comparison method for enhanced TOPS models
nd: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a...
Mallika Veeramalai, David Gilbert, Gabriel Valient...