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    BMCBI
    2008
    118views more  BMCBI 2008»
    Evaluation of phylogenetic footprint discovery for predicting bacterial cis-regulatory elements and revealing their evolution
    13 years 5 months ago
    Evaluation of phylogenetic footprint discovery for predicting bacterial cis-regulatory elements and revealing their evolution
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    Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...
    Rekin's Janky, Jacques van Helden
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    BMCBI
    2005
    152views more  BMCBI 2005»
    Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
    13 years 5 months ago
    Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
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    Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
    Markus Wistrand, Erik L. L. Sonnhammer
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    BMCBI
    2007
    179views more  BMCBI 2007»
    Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data
    13 years 5 months ago
    Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data
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    Background: The wide use of Affymetrix microarray in broadened fields of biological research has made the probeset annotation an important issue. Standard Affymetrix probeset anno...
    Hui Yu, Feng Wang, Kang Tu, Lu Xie, Yuan-Yuan Li, ...
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    BMCBI
    2005
    198views more  BMCBI 2005»
    Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
    13 years 5 months ago
    Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
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    Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
    Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
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    BMCBI
    2008
    126views more  BMCBI 2008»
    c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
    13 years 5 months ago
    c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
    Download  www.biomedcentral.com
    Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
    Katerina Kechris, Hao Li
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