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BMCBI
2007
102views more  BMCBI 2007»
13 years 5 months ago
Identification of homologs in insignificant blast hits by exploiting extrinsic gene properties
Background: Homology is a key concept in both evolutionary biology and genomics. Detection of homology is crucial in fields like the functional annotation of protein sequences and...
Jos Boekhorst, Berend Snel
BMCBI
2008
111views more  BMCBI 2008»
13 years 5 months ago
Information-based methods for predicting gene function from systematic gene knock-downs
Background: The rapid annotation of genes on a genome-wide scale is now possible for several organisms using high-throughput RNA interference assays to knock down the expression o...
Matthew T. Weirauch, Christopher K. Wong, Alexandr...
BMCBI
2010
193views more  BMCBI 2010»
13 years 5 months ago
Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
Background: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-...
Jakub Mieczkowski, Magdalena E. Tyburczy, Michal D...