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CBMS
2006
IEEE
13 years 6 months ago
Incorporating Gene Ontology in Clustering Gene Expression Data
In this paper we consider a general framework for clustering expression data that permits integration of various biological data sources through combination of corresponding dissi...
Rafal Kustra, Adam Zagdanski
CSB
2004
IEEE
173views Bioinformatics» more  CSB 2004»
13 years 8 months ago
Gene Ontology Friendly Biclustering of Expression Profiles
The soundness of clustering in the analysis of gene expression profiles and gene function prediction is based on the hypothesis that genes with similar expression profiles may imp...
Jinze Liu, Wei Wang 0010, Jiong Yang
ICASSP
2008
IEEE
13 years 10 months ago
Probabilistic framework for gene expression clustering validation based on gene ontology and graph theory
Based on the correlation between expression and ontologydriven gene similarity, we incorporate functional annotations into gene expression clustering validation. A probabilistic f...
Yinyin Yuan, Chang-Tsun Li
ICASSP
2011
IEEE
12 years 8 months ago
Biological pathway inference using manifold embedding
Disease occurs due to aberrant modulation of biological pathways. Identification of activated gene pathways from gene expression data is an important problem. In this work, we de...
Arvind Rao, Alfred O. Hero
BIBE
2004
IEEE
179views Bioinformatics» more  BIBE 2004»
13 years 8 months ago
Incorporating Ontology-Driven Similarity Knowledge into Functional Genomics: An Exploratory Study
This research explores the feasibility of semantic similarity approaches to supporting predictive tasks in functional genomics. It aims to establish potential relationships betwee...
Francisco Azuaje, Olivier Bodenreider