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OOPSLA
2005
Springer
13 years 11 months ago
Exploring the acceptability envelope
An acceptability envelope is a region of imperfect but acceptable software systems surrounding a given perfect system. Explicitly targeting the acceptability envelope during devel...
Martin C. Rinard, Cristian Cadar, Huu Hai Nguyen
BMCBI
2010
132views more  BMCBI 2010»
13 years 6 months ago
Protein docking by Rotation-Based Uniform Sampling (RotBUS) with fast computing of intermolecular contact distance and residue d
Background: Protein-protein interactions are fundamental for the majority of cellular processes and their study is of enormous biotechnological and therapeutic interest. In recent...
Albert Solernou, Juan Fernández-Recio
BMCBI
2006
86views more  BMCBI 2006»
13 years 6 months ago
MCALIGN2: Faster, accurate global pairwise alignment of non-coding DNA sequences based on explicit models of indel evolution
Background: Non-coding DNA sequences comprise a very large proportion of the total genomic content of mammals, most other vertebrates, many invertebrates, and most plants. Unravel...
Jun Wang, Peter D. Keightley, Toby Johnson
ML
2006
ACM
13 years 6 months ago
Universal parameter optimisation in games based on SPSA
Most game programs have a large number of parameters that are crucial for their performance. While tuning these parameters by hand is rather difficult, efficient and easy to use ge...
Levente Kocsis, Csaba Szepesvári
BMCBI
2007
102views more  BMCBI 2007»
13 years 6 months ago
Identification of homologs in insignificant blast hits by exploiting extrinsic gene properties
Background: Homology is a key concept in both evolutionary biology and genomics. Detection of homology is crucial in fields like the functional annotation of protein sequences and...
Jos Boekhorst, Berend Snel