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JCP
2006
157views more  JCP 2006»
13 years 5 months ago
CF-GeNe: Fuzzy Framework for Robust Gene Regulatory Network Inference
Most Gene Regulatory Network (GRN) studies ignore the impact of the noisy nature of gene expression data despite its significant influence upon inferred results. This paper present...
Muhammad Shoaib B. Sehgal, Iqbal Gondal, Laurence ...
BMCBI
2007
130views more  BMCBI 2007»
13 years 5 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
BMCBI
2010
172views more  BMCBI 2010»
13 years 5 months ago
Comparison of evolutionary algorithms in gene regulatory network model inference
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Alina Sîrbu, Heather J. Ruskin, Martin Crane
BMCBI
2007
144views more  BMCBI 2007»
13 years 5 months ago
Accelerated search for biomolecular network models to interpret high-throughput experimental data
Background: The functions of human cells are carried out by biomolecular networks, which include proteins, genes, and regulatory sites within DNA that encode and control protein e...
Suman Datta, Bahrad A. Sokhansanj
BMCBI
2010
110views more  BMCBI 2010»
13 years 5 months ago
TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach
Background: One of main aims of Molecular Biology is the gain of knowledge about how molecular components interact each other and to understand gene function regulations. Using mi...
Pietro Zoppoli, Sandro Morganella, Michele Ceccare...