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» Inferring Genetic Networks from Microarray Data
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BMCBI
2007
130views more  BMCBI 2007»
13 years 5 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
BMCBI
2008
130views more  BMCBI 2008»
13 years 5 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...
BMCBI
2005
189views more  BMCBI 2005»
13 years 5 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen
BMCBI
2010
167views more  BMCBI 2010»
13 years 5 months ago
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...