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BMCBI
2008
124views more  BMCBI 2008»
10 years 4 months ago
Inferring modules of functionally interacting proteins using the Bond Energy Algorithm
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
Ryosuke Watanabe, Enrique Morett, Edgar E. Vallejo
BMCBI
2010
142views more  BMCBI 2010»
10 years 4 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan
BMCBI
2005
169views more  BMCBI 2005»
10 years 4 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
BMCBI
2007
227views more  BMCBI 2007»
10 years 4 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
EVOW
2008
Springer
10 years 6 months ago
Protein Interaction Inference Using Particle Swarm Optimization Algorithm
Many processes in the cell involve interaction among the proteins and determination of the networks of such interactions is of immense importance towards the complete understanding...
Mudassar Iqbal, Alex Alves Freitas, Colin G. Johns...
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