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» Inferring modules of functionally interacting proteins using...
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BMCBI
2010
164views more  BMCBI 2010»
13 years 3 months ago
Investigating the validity of current network analysis on static conglomerate networks by protein network stratification
Background: A molecular network perspective forms the foundation of systems biology. A common practice in analyzing protein-protein interaction (PPI) networks is to perform networ...
Minlu Zhang, Long J. Lu
BMCBI
2008
128views more  BMCBI 2008»
13 years 3 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
BMCBI
2008
129views more  BMCBI 2008»
13 years 3 months ago
Triad pattern algorithm for predicting strong promoter candidates in bacterial genomes
Background: Bacterial promoters, which increase the efficiency of gene expression, differ from other promoters by several characteristics. This difference, not yet widely exploite...
Michael Dekhtyar, Amelie Morin, Vehary Sakanyan
SDM
2009
SIAM
192views Data Mining» more  SDM 2009»
14 years 24 days ago
Mining Cohesive Patterns from Graphs with Feature Vectors.
The increasing availability of network data is creating a great potential for knowledge discovery from graph data. In many applications, feature vectors are given in addition to g...
Arash Rafiey, Flavia Moser, Martin Ester, Recep Co...
BMCBI
2010
154views more  BMCBI 2010»
13 years 1 months ago
Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation
Background: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gen...
Andreas Kowarsch, Florian Blöchl, Sebastian B...