Sciweavers

16 search results - page 1 / 4
» Information transfer in signaling pathways: A study using co...
Sort
View
BMCBI
2008
138views more  BMCBI 2008»
13 years 4 months ago
Information transfer in signaling pathways: A study using coupled simulated and experimental data
Background: The topology of signaling cascades has been studied in quite some detail. However, how information is processed exactly is still relatively unknown. Since quite divers...
Jürgen Pahle, Anne K. Green, C. Jane Dixon, U...
JMLR
2010
105views more  JMLR 2010»
12 years 11 months ago
Evaluation of Signaling Cascades Based on the Weights from Microarray and ChIP-seq Data
In this study, we combined the ChIP-seq and the transcriptome data and integrated these data into signaling cascades. Integration was realized through a framework based on data- a...
Zerrin Isik, Volkan Atalay, Rengül Çet...
RECOMB
2010
Springer
13 years 11 months ago
Incremental Signaling Pathway Modeling by Data Integration
Constructing quantitative dynamic models of signaling pathways is an important task for computational systems biology. Pathway model construction is often an inherently incremental...
Geoffrey Koh, David Hsu, P. S. Thiagarajan
RECOMB
2001
Springer
13 years 8 months ago
Extracting structural information using time-frequency analysis of protein NMR data
High-throughput, data-directed computational protocols for Structural Genomics (or Proteomics) are required in order to evaluate the protein products of genes for structure and fu...
Christopher James Langmead, Bruce Randall Donald
BMCBI
2010
135views more  BMCBI 2010»
13 years 4 months ago
Detecting disease associated modules and prioritizing active genes based on high throughput data
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...