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BMCBI
2005
112views more  BMCBI 2005»
13 years 3 months ago
Integration of the Gene Ontology into an object-oriented architecture
Background: To standardize gene product descriptions, a formal vocabulary defined as the Gene Ontology (GO) has been developed. GO terms have been categorized into biological proc...
Daniel Shegogue, W. Jim Zheng
ER
2007
Springer
187views Database» more  ER 2007»
13 years 9 months ago
Metamodeling Integration Architecture for Open Biomedical Ontologies: The GO Extensions' Case Study
New technologies used in biology are generating huge quantities of data; up to two petabytes of overall data are to be expected by the end of the decade. Modern biology also has t...
Marie-Noëlle Terrasse, Marinette Savonnet, Er...
BMCBI
2005
159views more  BMCBI 2005»
13 years 3 months ago
Columba: an integrated database of proteins, structures, and annotations
Background: Structural and functional research often requires the computation of sets of protein structures based on certain properties of the proteins, such as sequence features,...
Silke Trißl, Kristian Rother, Heiko Mül...
BMCBI
2008
145views more  BMCBI 2008»
13 years 3 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
BMCBI
2010
146views more  BMCBI 2010»
13 years 3 months ago
Booly: a new data integration platform
Background: Data integration is an escalating problem in bioinformatics. We have developed a web tool and warehousing system, Booly, that features a simple yet flexible data model...
Long H. Do, Francisco F. Esteves, Harvey J. Karten...