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BMCBI
2010
100views more  BMCBI 2010»
13 years 4 months ago
A robust method for estimating gene expression states using Affymetrix microarray probe level data
Background: Microarray technology is a high-throughput method for measuring the expression levels of thousand of genes simultaneously. The observed intensities combine a non-speci...
Megu Ohtaki, Keiko Otani, Keiko Hiyama, Naomi Kame...
BMCBI
2006
126views more  BMCBI 2006»
13 years 4 months ago
Differential prioritization between relevance and redundancy in correlation-based feature selection techniques for multiclass ge
Background: Due to the large number of genes in a typical microarray dataset, feature selection looks set to play an important role in reducing noise and computational cost in gen...
Chia Huey Ooi, Madhu Chetty, Shyh Wei Teng
BMCBI
2006
103views more  BMCBI 2006»
13 years 4 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
BMCBI
2007
159views more  BMCBI 2007»
13 years 4 months ago
Detecting differential expression in microarray data: comparison of optimal procedures
Background: Many procedures for finding differentially expressed genes in microarray data are based on classical or modified t-statistics. Due to multiple testing considerations, ...
Elena Perelman, Alexander Ploner, Stefano Calza, Y...
BMCBI
2004
150views more  BMCBI 2004»
13 years 4 months ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...