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    BMCBI
    2008
    98views more  BMCBI 2008»
    Empirical Bayes models for multiple probe type microarrays at the probe level
    13 years 4 months ago
    Empirical Bayes models for multiple probe type microarrays at the probe level
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    Background: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are...
    Magnus Åstrand, Petter Mostad, Mats Rudemo
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    BMCBI
    2008
    138views more  BMCBI 2008»
    M-BISON: Microarray-based integration of data sources using networks
    13 years 4 months ago
    M-BISON: Microarray-based integration of data sources using networks
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    Background: The accurate detection of differentially expressed (DE) genes has become a central task in microarray analysis. Unfortunately, the noise level and experimental variabi...
    Bernie J. Daigle Jr., Russ B. Altman
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    BMCBI
    2010
    135views more  BMCBI 2010»
    Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
    13 years 4 months ago
    Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
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    Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
    Marc Hulsman, Anouk Mentink, Eugene P. van Someren...
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    BMCBI
    2008
    124views more  BMCBI 2008»
    A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
    13 years 4 months ago
    A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
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    Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
    Huanying Ge, Chao Cheng, Lei M. Li
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    BMCBI
    2010
    91views more  BMCBI 2010»
    Algorithm-driven Artifacts in median polish summarization of Microarray data
    13 years 4 months ago
    Algorithm-driven Artifacts in median polish summarization of Microarray data
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    Background: High-throughput measurement of transcript intensities using Affymetrix type oligonucleotide microarrays has produced a massive quantity of data during the last decade....
    Federico M. Giorgi, Anthony M. Bolger, Marc Lohse,...
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