teps. First, we abstracted protein interactions onto orthologous cluster links. For a given source interaction, if both proteins belonged to a cluster, we constructed a link betwee...
Magali Michaut, Samuel Kerrien, Luisa Montecchi-Pa...
: The recent availability of large data sets of protein- protein-interactions (PPIs) from various species offers new opportunities for functional genomics and proteomics. We descri...
Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
Background: Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles ...
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...