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BMCBI
2007
110views more  BMCBI 2007»
13 years 4 months ago
Interpretation of multiple probe sets mapping to the same gene in Affymetrix GeneChips
Background: Affymetrix GeneChip technology enables the parallel observations of tens of thousands of genes. It is important that the probe set annotations are reliable so that bio...
Maria A. Stalteri, Andrew P. Harrison
BMCBI
2010
193views more  BMCBI 2010»
13 years 4 months ago
Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
Background: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-...
Jakub Mieczkowski, Magdalena E. Tyburczy, Michal D...
BMCBI
2007
160views more  BMCBI 2007»
13 years 4 months ago
Establishing a major cause of discrepancy in the calibration of Affymetrix GeneChips
Background: Affymetrix GeneChips are a popular platform for performing whole-genome experiments on the transcriptome. There are a range of different calibration steps, and users a...
Andrew P. Harrison, Caroline E. Johnston, Christin...
BMCBI
2005
144views more  BMCBI 2005»
13 years 4 months ago
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in
Background: Comparison of data produced on different microarray platforms often shows surprising discordance. It is not clear whether this discrepancy is caused by noisy data or b...
Scott L. Carter, Aron C. Eklund, Brigham H. Mecham...
BMCBI
2007
111views more  BMCBI 2007»
13 years 4 months ago
Novel definition files for human GeneChips based on GeneAnnot
Background: Improvements in genome sequence annotation revealed discrepancies in the original probeset/gene assignment in Affymetrix microarray and the existence of differences be...
Francesco Ferrari, Stefania Bortoluzzi, Alessandro...