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» Investigating a Correlation between Subcellular Localization...
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BMCBI
2005
150views more  BMCBI 2005»
13 years 4 months ago
Discover protein sequence signatures from protein-protein interaction data
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...
BMCBI
2010
148views more  BMCBI 2010»
13 years 4 months ago
Analysis of interactions between ribosomal proteins and RNA structural motifs
Background: One important goal of structural bioinformatics is to recognize and predict the interactions between protein binding sites and RNA. Recently, a comprehensive analysis ...
Giovanni Ciriello, Claudio Gallina, Concettina Gue...
BMCBI
2010
97views more  BMCBI 2010»
13 years 4 months ago
Incorporating significant amino acid pairs to identify O-linked glycosylation sites on transmembrane proteins and non-transmembr
Background: While occurring enzymatically in biological systems, O-linked glycosylation affects protein folding, localization and trafficking, protein solubility, antigenicity, bi...
Shu-An Chen, Tzong-Yi Lee, Yu-Yen Ou
BMCBI
2006
242views more  BMCBI 2006»
13 years 4 months ago
Predicting residue-wise contact orders in proteins by support vector regression
Background: The residue-wise contact order (RWCO) describes the sequence separations between the residues of interest and its contacting residues in a protein sequence. It is a ne...
Jiangning Song, Kevin Burrage
BMCBI
2006
172views more  BMCBI 2006»
13 years 4 months ago
Prediction of cis/trans isomerization in proteins using PSI-BLAST profiles and secondary structure information
Background: The majority of peptide bonds in proteins are found to occur in the trans conformation. However, for proline residues, a considerable fraction of Prolyl peptide bonds ...
Jiangning Song, Kevin Burrage, Zheng Yuan, Thomas ...