40 search results - page 2 / 8 » Investigating the effect of paralogs on microarray gene-set ... |
BMCBI
2011
12 years 11 months ago
2011
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
BMCBI
2010
13 years 4 months ago
2010
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
BMCBI
2005
13 years 4 months ago
2005
Background: Numerous nonparametric approaches have been proposed in literature to detect differential gene expression in the setting of two user-defined groups. However, there is ...
BMCBI
2005
13 years 4 months ago
2005
Background: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for ...
BMCBI
2004
13 years 4 months ago
2004
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...