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BIOINFORMATICS
2006
96views more  BIOINFORMATICS 2006»
13 years 4 months ago
Joint estimation of calibration and expression for high-density oligonucleotide arrays
Motivation: The need for normalization in microarray experiments has been well documented in the literature. Currently, most analysis methods treat normalization and analysis as a...
Ann L. Oberg, Douglas W. Mahoney, Karla V. Ballman...
BMCBI
2008
124views more  BMCBI 2008»
13 years 5 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li
BMCBI
2010
165views more  BMCBI 2010»
13 years 5 months ago
Filtering, FDR and power
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Maarten van Iterson, Judith M. Boer, Renée ...