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» Kernel Based Functional Gene Grouping
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BMCBI
2006
165views more  BMCBI 2006»
13 years 5 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
BMCBI
2006
207views more  BMCBI 2006»
13 years 5 months ago
A new measure for functional similarity of gene products based on Gene Ontology
Background: Gene Ontology (GO) is a standard vocabulary of functional terms and allows for coherent annotation of gene products. These annotations provide a basis for new methods ...
Andreas Schlicker, Francisco S. Domingues, Jö...
JIPS
2007
134views more  JIPS 2007»
13 years 5 months ago
An Efficient Functional Analysis Method for Micro-array Data Using Gene Ontology
: Microarray data includes tens of thousands of gene expressions simultaneously, so it can be effectively used in identifying the phenotypes of diseases. However, the retrieval of ...
Dong-wan Hong, Jong-keun Lee, Sung-soo Park, Sang-...
BMCBI
2008
228views more  BMCBI 2008»
13 years 5 months ago
Adaptive diffusion kernel learning from biological networks for protein function prediction
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...
Liang Sun, Shuiwang Ji, Jieping Ye
BMCBI
2005
124views more  BMCBI 2005»
13 years 5 months ago
ErmineJ: Tool for functional analysis of gene expression data sets
Background: It is common for the results of a microarray study to be analyzed in the context of biologically-motivated groups of genes such as pathways or Gene Ontology categories...
Homin K. Lee, William Braynen, Kiran Keshav, Paul ...